Cancer Cytogenetics: Methods and Protocols

This volume provides readers with detailed protocols covering the
main cancer cytogenetics techniques needed for clinical utilization and
research purposes. The chapters in this book cover topics such as
chromosome preparation for myeloid malignancies; chromosome bandings;
fluorescence in situ hybridization probe preparation; array-based
comparative genomic hybridization; and cytogenetic nomenclature and
reporting. The updated reviews on chromosomal abnormalities in
hematological malignancies are excellent guides for cytogenetics data
interpretations and specific malignant diseases correlation. Written in
the highly successful Methods in Molecular Biology series format,
chapters include introductions to their respective topics, lists of the
necessary materials and reagents, step-by-step, readily reproducible
laboratory protocols, and tips on troubleshooting and avoiding known
pitfalls.